Director of Clinical Science and Applied Research

What is Motif?

Motif is a medical device startup based in Houston, Texas. We are designing and developing minimally invasive electronic solutions for serious mental health conditions. Powered by our patent-pending methods for wireless power and data transmission, our goal is to create the smallest implantable brain stimulator to treat people with mental health disorders.

We are an early-stage startup with funding from venture capital firms, grants, and private angel and founder investments.

Motif’s technology stack consists of a small implant that is wirelessly powered via magnetic fields from an external wearable transmitter, configured and controlled from a programming interface. It delivers novel stimulation therapy to cortical targets and will evolve to record biomarkers of symptoms, disease state, and therapy response.

Where are we going?

We are currently completing the development of our first minimally invasive neural stimulation system and preparing for future versions with additional functionality based on our platform technology.

About the job

We are seeking a cross-functional strategic leader to oversee clinical evidence generation and external research partnerships. If you have a passion for translating early-stage neurotechnology into therapies that reach patients, apply now to be part of our dedicated team. Lead the clinical roadmap from early feasibility through reimbursement while shaping the scientific narrative for a new class of psychiatric therapy.

Job Location: Remote with occasional visits to Motif Headquarters in Houston, Texas

Does this sound like you?

Do you believe openness and honesty are key to team success?

Do you enjoy learning and are curious about how and why things work?

Do you like challenging the conventional way of doing things to find efficiencies and new ways of working?

If yes to the above, then come work with Motif! We are highly dedicated people with a passion for neurotechnology, clinical product development, and putting the patient first. We are looking for people with the same energy who will thrive in a high growth - high autonomy environment.

In this role, you will:

Develop and own the clinical roadmap

Define the end-to-end evidence generation strategy from early feasibility studies through to successful reimbursement decisions

Integrate regulatory and reimbursement requirements into study design to ensure clinical data supports both approval and coverage

Partner with leadership to align the clinical roadmap with company strategy, financing milestones, and product development timelines

Oversee clinical development projects and grants

Provide oversight of active clinical studies, ensuring programs are delivered on time, on budget, and to protocol

Identify, secure, and manage non-dilutive funding sources, including federal grants and foundation support for evidence development (clinical and preclinical) programs

Oversee grant-funded programs end-to-end, including reporting, milestone tracking, and renewals

Represent the company externally and build the scientific community

Represent the company at scientific and medical meetings, presenting data and shaping the clinical narrative for our platform

Build and maintain peer-level relationships with key opinion leaders in psychiatry, neuromodulation, and related fields

Establish and manage external research partnerships with academic investigators and clinical collaborators

This is not an exhaustive list of duties and you may be asked to perform different tasks if your role within or the objectives of the organization changes.

To be considered, you will need:

10+ years of experience in clinical development within the medical device, pharmaceutical, or biotech industry, with progressive leadership responsibility

Demonstrated experience leading clinical studies from protocol design through execution, including at least one study that supported a regulatory submission or market approval

Experience directly managing clinical, scientific, or medical affairs teams, and a track record of representing an organization at scientific meetings

To be able to travel to Houston, TX for onsite meetings (approximately ~4-5 times per year) and to other scientific conferences and/or clinical meetings

It is a bonus if you have:

Experience in active implantable medical devices, neuromodulation, or neurostimulation therapies

Clinical or research background in psychiatry, depression, or related mental health indications

Advanced degree (MD, PhD, or equivalent) and a record of peer-reviewed publications or successful grant applications

Work Authorization Notice

Motif Neurotech hires only individuals who are authorized to work in the United States. At this time, visa sponsorship is not offered for this role.

Benefits*

Medical, dental, and vision insurance for you and your dependents

Participation in our 401k plan

Unlimited PTO

The chance to work with an incredible group of people working towards a common goal for a better future

We envision a world where everyone with a mental health disorder can get well and stay well, regardless of who you are, where you live, or how much money you make, and we are excited to build that future with you.

Let’s use our powers for good.

Motif Neurotech is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability status, or any other protected class status.

*for regular full-time, exempt, salaried US employees

Department: Clinical.

ATS provider: Greenhouse.